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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1995836Generated: October 31, 2026

3,4,5,6-Tetrahydrophthalic anhydride → 3-Pyridinamine, 6-[(4-chlorophenyl)methoxy]-

https://huagongshe.com/reaction/1995836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5,6-Tetrahydrophthalic anhydrideHCID 12475—
Reactant4-Chlorobenzyl alcoholHCID 13397—
Reactant2-Chloro-5-nitropyridineHCID 78308—
Product3-Pyridinamine, 6-[(4-chlorophenyl)methoxy]-HCID 580409—
ProductHCID 20486093HCID 20486093—

Reaction Steps

The compound, 5-amino-2-(4-chlorobenzyloxy)pyridine is prepared from 2-chloro-5-nitropyridine and 4-chlorobenzyl alcohol and then reacted with 3,4,5,6-tetrahydrophthalic anhydride using the procedure of Example 1 to yield N-[2-(4-chlorobenzyloxy)-5-pyridyl]-3,4,5,6-tetrahydrophthalimide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04406689
Source datasetuspto-grants-1983_09
ORD IDord-0979a3d43ae24627a4c884401057a62b
Source noteuspto-grants-1983_09