Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-[(4-Chlorophenyl)methoxy]-2-nitropyridine → 5-[(4-Chlorophenyl)methoxy]pyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-[(4-Chlorophenyl)methoxy]-2-nitropyridine | HCID 20486129 | — |
| 촉매 | Water | HCID 962 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-[(4-Chlorophenyl)methoxy]pyridin-2-amine | HCID 20486112 | — |
반응 단계
A mixture of 5-(4-chlorobenzyloxy)-2-nitropyridine (0.5 g), Na2S (0.25 g) and methanol (12 ml) is heated to reflux for about 3 hours. Then, a few drops of water is added and refluxing continued about 15 hours. After cooling, the reaction is diluted with methanol, filtered through celite and stripped. The concentrate is taken up in CHCl3, washed with water, dried and stripped giving 2-amino-5-(4-chlorobenzyloxy)pyridine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04406689 |
| 출처 데이터셋 | uspto-grants-1983_09 |
| ORD ID | ord-d0b88793ae6c414990b04c5246241a74 |
| 출처 메모 | uspto-grants-1983_09 |