Phosgene → HCID 20486082, compound

HRID 1995852Notes

Reaction equation

HRID 1995852 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][NH:7]1)=[O:5])[CH3:2].[C:12](Cl)([Cl:14])=[O:13]>>[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][N:7]1[C:12]([Cl:14])=[O:13])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 6371PhosgeneHCID 30143771(2H)-Pyridazinecarboxylic acid, tetrahydro-, ethyl ester

Product 1

HCID 20486082HCID 20486082, compound

Procedure

In the same way, 4-[2-(4-chlorobenzyloxy)-5-pyridyl]-1,2-tetramethylenetriazolidine-3,5-dione is prepared by reacting N-ethoxycarbonylhexahydropyridazine with phosgene to give N-ethoxycarbonyl-N'-chlorocarbonylhexahydropyridazine, which is then reacted with 5-amino-2-(4-chlorobenzyloxy)pyridine.

Sources & evidence

ORD record
ord-d749441e408d4280972d367e1a163ab7
Source dataset
uspto-grants-1983_09
Patent number
US04406689

Reaction notes

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