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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1995953Generated: October 26, 2026

Dimethyl Sulfate → 5-bromo-7-fluoro-1-methyl-1H-indazole

https://huagongshe.com/reaction/1995953

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfateHCID 6497—
Reactant5-Bromo-7-fluoro-1H-indazoleHCID 66793110—
ReagentN'''-(1,1-Dimethylethyl)-N,N',N''-tris(tris(dimethylamino)phosphoranylidene)phosphorimidic triamideHCID 4339838—
SolventTetrahydrofuranHCID 8028—
Product5-bromo-7-fluoro-1-methyl-1H-indazoleHCID 84056882—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-569240a8618b461b82f432ad3ef1f9c6
Source note39k HTE dataset from Pfizer