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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1996015Generated: October 26, 2026

Dimethyl Sulfate → 5-Bromo-7-fluoro-2-methyl-2H-indazole

https://huagongshe.com/reaction/1996015

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfateHCID 6497—
Reactant5-Bromo-7-fluoro-1H-indazoleHCID 66793110—
ReagentPhosphazene base P1-t-BuHCID 4195269—
Solvent2-Methyl-2-butanolHCID 6405—
Product5-Bromo-7-fluoro-2-methyl-2H-indazoleHCID 122544572—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3d09a1c6959b4441b0cf862149b4cf39
Source note39k HTE dataset from Pfizer