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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1996224Generated: November 1, 2026

Dimethyl Sulfate → 5-Bromo-7-fluoro-2-methyl-2H-indazole

https://huagongshe.com/reaction/1996224

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfateHCID 6497—
Reactant5-Bromo-7-fluoro-1H-indazoleHCID 66793110—
ReagentPhosphazene base P2-t-Bu solutionHCID 4275357—
SolventTolueneHCID 1140—
Product5-Bromo-7-fluoro-2-methyl-2H-indazoleHCID 122544572—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-1c1f9f00978a46a9a0d7ea315b434b37
Source note39k HTE dataset from Pfizer