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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1996236Generated: October 31, 2026

Dimethyl Sulfate → 5-bromo-7-fluoro-1-methyl-1H-indazole

https://huagongshe.com/reaction/1996236

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfateHCID 6497—
Reactant5-Bromo-7-fluoro-1H-indazoleHCID 66793110—
ReagentLithium magnesium 2,2,6,6-tetramethylpiperidin-1-ide dichlorideHCID 25150783—
SolventDimethylformamideHCID 6228—
Product5-bromo-7-fluoro-1-methyl-1H-indazoleHCID 84056882—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-8a9031ae5de24b6da3bf1bf10ec1385f
Source note39k HTE dataset from Pfizer