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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1996287Generated: October 31, 2026

Dimethyl Sulfate → 5-Bromo-7-fluoro-2-methyl-2H-indazole

https://huagongshe.com/reaction/1996287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfateHCID 6497—
Reactant5-Bromo-7-fluoro-1H-indazoleHCID 66793110—
ReagentCaesium hydroxide--water (1/1/1)HCID 23679066—
Solvent2-Methyl-2-butanolHCID 6405—
Product5-Bromo-7-fluoro-2-methyl-2H-indazoleHCID 122544572—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-2a5109e95e064bbe80ce8d0385b9f7f0
Source note39k HTE dataset from Pfizer