Methanol → 2-Fluoro-3-(propylsulfonamido)benzoic acid

HRID 199838Notes

Reaction equation

HRID 199838 reaction equation
[CH3:19][OH:20].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:12][S:13](=[O:14])(=[O:15])[CH2:16][CH2:17][CH3:18])[c:6]([F:11])[c:7]1[C:8](=[O:9])[OH:10].[OH-:21].[OH-:23].[Pd+2:22]>>[cH:2]1[cH:3][cH:4][c:5]([NH:12][S:13](=[O:14])(=[O:15])[CH2:16][CH2:17][CH3:18])[c:6]([F:11])[c:7]1[C:8](=[O:9])[OH:10]

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 580875006-Chloro-2-fluoro-3-(propane-1-sulfonamido)benzoic acid

Product 1

HCID 580865772-Fluoro-3-(propylsulfonamido)benzoic acid

Sources & evidence

ORD record
ord-1c1f097ed1b84626b7a6b38bf0907aa5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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