1,4-Dioxane → Tert-butyl 3-(2-((2-cyano-6-(trifluoromethyl)quinolin-4-yl)amino)acetamido)azetidine-1-carboxylate
Reaction equation
[NH2:18][CH2:19][C:20](=[O:21])[NH:22][CH:23]1[CH2:24][N:25]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:26]1.[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[OH:1][c:2]1[cH:3][c:4]([C:16]#[N:17])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12>>[c:2]1([NH:18][CH2:19][C:20](=[O:21])[NH:22][CH:23]2[CH2:24][N:25]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:26]2)[cH:3][c:4]([C:16]#[N:17])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12Participants
4
Sources & evidence
- ORD record
- ord-05f4002ae6f942faa156ebcc9f8df31f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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