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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1999793Generated: November 1, 2026

2-Chloroethanol → 3-Methyl-4-nitro-1H-pyrazole-1-ethanol

https://huagongshe.com/reaction/1999793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloroethanolHCID 34—
ReactantHCID 178434564HCID 178434564—
Reagent2-Propanol, 2-methyl-, lithium salt (1:1)HCID 23664764—
SolventDimethylformamideHCID 6228—
Product3-Methyl-4-nitro-1H-pyrazole-1-ethanolHCID 67076052—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-522a258dd4314a13aea3c6612cf8e134
Source note39k HTE dataset from Pfizer