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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2000389Generated: October 25, 2026

Ethyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylate → ethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylate

https://huagongshe.com/reaction/2000389

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylateHCID 23630921—
Reactant2,4-Dichloro-5-(pyridin-2-yl)benzoic acidHCID 118497090—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Fluoro-1-methylpyridinium p-toluenesulfonateHCID 171631—
SolventDimethylformamideHCID 6228—
Productethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylateHCID 118497071—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-5f090c45590d475b863f042e82998d3c
Source note39k HTE dataset from Pfizer