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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2000469Generated: October 29, 2026

Ethyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylate → ethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylate

https://huagongshe.com/reaction/2000469

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylateHCID 23630921—
Reactant2,4-Dichloro-5-(pyridin-2-yl)benzoic acidHCID 118497090—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Fluoro-1,3-dimethylpyridinium tosylateHCID 6453802—
SolventTetrahydrofuranHCID 8028—
Productethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylateHCID 118497071—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-ea3717ca6b8e490d89e0aa2f83a02107
Source note39k HTE dataset from Pfizer