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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2000514Generated: October 30, 2026

Ethyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylate → ethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylate

https://huagongshe.com/reaction/2000514

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylateHCID 23630921—
Reactant2,4-Dichloro-5-(pyridin-2-yl)benzoic acidHCID 118497090—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventTetrahydrofuranHCID 8028—
Productethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylateHCID 118497071—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-22db95ea6afa49d783bc9da1324f2097
Source note39k HTE dataset from Pfizer