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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2000996Generated: October 30, 2026

Tert-Butyl isocyanide → HCID 178440949, compound

https://huagongshe.com/reaction/2000996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-Butyl isocyanideHCID 23577—
Reactant5-Bromo-2-tert-butylpyridineHCID 21041308—
ReactantHCID 178419779HCID 178419779—
ReagentLithium HexamethyldisilazideHCID 2733832—
CatalystBinap, (A+-)-HCID 634876—
SolventTolueneHCID 1140—
ProductHCID 178440949HCID 178440949—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-a74d6cf1162946e08ef5c3370dc7d54c
Source note39k HTE dataset from Pfizer