HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2001350Generated: October 31, 2026
Triethylsilicon → tert-butyl 6-formyl-8-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate
https://huagongshe.com/reaction/2001350
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylsilicon | HCID 6327258 | — |
| Reactant | 1,1,3-Trioxo-1,3-dihydro-2H-1lambda~6~,2-benzothiazole-2-carbaldehyde | HCID 54671689 | — |
| Reactant | tert-butyl 6-bromo-8-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate | HCID 132189892 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Catalyst | (1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine | HCID 6612782 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | tert-butyl 6-formyl-8-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate | HCID 132190424 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-e355428eb16a4ad6aae2ea463b456108 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
