HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2001361Generated: October 27, 2026
Triethylsilicon → tert-butyl 6-formyl-8-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate
https://huagongshe.com/reaction/2001361
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylsilicon | HCID 6327258 | — |
| Reactant | 1,1,3-Trioxo-1,3-dihydro-2H-1lambda~6~,2-benzothiazole-2-carbaldehyde | HCID 54671689 | — |
| Reactant | tert-butyl 6-bromo-8-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate | HCID 132189892 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Catalyst | 1,2-Cyclohexanediamine, N1,N2-bis[[2-(diphenylphosphino)phenyl]methyl]-, (1S,2S)- | HCID 11051123 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | tert-butyl 6-formyl-8-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate | HCID 132190424 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-b76aaf80062a42898f0ec70bff9f9fe0 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
