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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2001503Generated: October 30, 2026

Tert-Butyl isocyanide → HCID 178440949, compound

https://huagongshe.com/reaction/2001503

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-Butyl isocyanideHCID 23577—
Reactant5-Bromo-2-tert-butylpyridineHCID 21041308—
ReactantHCID 178419779HCID 178419779—
ReagentHydrochloric AcidHCID 313—
ReagentPotassium CarbonateHCID 11430—
Catalystpalladium(II) acetateHCID 167845—
CatalystBis(cyclopentyl(diphenyl)phosphane);ironHCID 24721398—
SolventTolueneHCID 1140—
ProductHCID 178440949HCID 178440949—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-ca667349a28e4f6187722ca8825d1f9e
Source note39k HTE dataset from Pfizer