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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2001552Generated: November 1, 2026

Methanol → Methyl 3-oxocyclopent-1-enecarboxylate

https://huagongshe.com/reaction/2001552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant1,1,3-Trioxo-1,3-dihydro-2H-1lambda~6~,2-benzothiazole-2-carbaldehydeHCID 54671689—
Reactant(3-Oxocyclopenten-1-yl) 4-methylbenzenesulfonateHCID 86196686—
ReagentSodium BicarbonateHCID 516892—
Catalystpalladium(II) acetateHCID 167845—
CatalystBinap, (A+-)-HCID 634876—
SolventMethanolHCID 887—
ProductMethyl 3-oxocyclopent-1-enecarboxylateHCID 11029917—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-dd0b1af3fcb7418a9ca5dce0125468c3
Source note39k HTE dataset from Pfizer