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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2001913Generated: October 29, 2026

Triethylsilicon → 1-Oxoisoindoline-4-carbaldehyde

https://huagongshe.com/reaction/2001913

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylsiliconHCID 6327258—
Reactant4-Bromoisoindolin-1-oneHCID 21907509—
Reactant1,1,3-Trioxo-1,3-dihydro-2H-1lambda~6~,2-benzothiazole-2-carbaldehydeHCID 54671689—
ReagentPotassium CarbonateHCID 11430—
CatalystTetrakis(triphenylphosphine)palladiumHCID 11979704—
SolventDimethylformamideHCID 6228—
Product1-Oxoisoindoline-4-carbaldehydeHCID 72213812—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-37d4ae6c7f7d455ea03ab11470f4b48d
Source note39k HTE dataset from Pfizer