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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2001949Generated: October 29, 2026

Carbon Monoxide → 1-Oxoisoindoline-4-carbaldehyde

https://huagongshe.com/reaction/2001949

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon MonoxideHCID 281—
ReactantTriethylsiliconHCID 6327258—
Reactant4-Bromoisoindolin-1-oneHCID 21907509—
ReagentSodium BicarbonateHCID 516892—
CatalystHCID 178422001HCID 178422001—
SolventDimethylacetamideHCID 31374—
Product1-Oxoisoindoline-4-carbaldehydeHCID 72213812—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-dffac246318841ca9a8c0397e403858c
Source note39k HTE dataset from Pfizer