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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002004Generated: October 29, 2026

Carbon Monoxide → 1-Oxoisoindoline-4-carbaldehyde

https://huagongshe.com/reaction/2002004

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon MonoxideHCID 281—
ReactantTriethylsiliconHCID 6327258—
Reactant4-Bromoisoindolin-1-oneHCID 21907509—
ReagentSodium BicarbonateHCID 516892—
CatalystBis(tri-tert-butylphosphine)palladium(0)HCID 2734558—
SolventTetrahydrofuranHCID 8028—
Product1-Oxoisoindoline-4-carbaldehydeHCID 72213812—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-1f077f630e884ec489c41ddd00a2990b
Source note39k HTE dataset from Pfizer