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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002166Generated: October 30, 2026

Carbon Monoxide → Methyl 3-oxocyclopent-1-enecarboxylate

https://huagongshe.com/reaction/2002166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon MonoxideHCID 281—
ReactantMethanolHCID 887—
Reactant(3-Oxocyclopenten-1-yl) 4-methylbenzenesulfonateHCID 86196686—
ReagentSodium bis(trimethylsilyl)amideHCID 2724254—
Catalystpalladium(II) acetateHCID 167845—
CatalystHCID 178420546HCID 178420546—
SolventMethanolHCID 887—
ProductMethyl 3-oxocyclopent-1-enecarboxylateHCID 11029917—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-2ee00d9548b94d63b0e78bf1087771d7
Source note39k HTE dataset from Pfizer