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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002412Generated: November 1, 2026

Carbon Monoxide → Methyl 3-oxocyclopent-1-enecarboxylate

https://huagongshe.com/reaction/2002412

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon MonoxideHCID 281—
ReactantMethanolHCID 887—
Reactant(3-Oxocyclopenten-1-yl) 4-methylbenzenesulfonateHCID 86196686—
ReagentDiisopropylethylamineHCID 81531—
Catalystpalladium(II) acetateHCID 167845—
Catalyst1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 636044—
SolventTolueneHCID 1140—
ProductMethyl 3-oxocyclopent-1-enecarboxylateHCID 11029917—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-b0f5cb8e5d5747de96b7b9d89c52fa00
Source note39k HTE dataset from Pfizer