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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002418Generated: November 2, 2026

Carbon Monoxide → Methyl 3-oxocyclopent-1-enecarboxylate

https://huagongshe.com/reaction/2002418

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon MonoxideHCID 281—
ReactantMethanolHCID 887—
Reactant(3-Oxocyclopenten-1-yl) 4-methylbenzenesulfonateHCID 86196686—
ReagentDiisopropylethylamineHCID 81531—
Catalystpalladium(II) acetateHCID 167845—
Catalyst(1,1'-Binaphthalen)-2-yldi-tert-butylphosphineHCID 2734941—
SolventTolueneHCID 1140—
ProductMethyl 3-oxocyclopent-1-enecarboxylateHCID 11029917—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-b7c20e666848410cb2727351ee420fc7
Source note39k HTE dataset from Pfizer