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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002646Generated: November 2, 2026

1-Methyl-1H-indazole-6-boronic acid → US10308615, Example 137

https://huagongshe.com/reaction/2002646

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-indazole-6-boronic acidHCID 44118215—
ReactantN-(5-Bromo-2-pyrimidinyl)-5-pyrimidinemethanamineHCID 83333413—
ReagentDiisopropylethylamineHCID 81531—
Catalystpalladium(II) acetateHCID 167845—
CatalystHCID 178454858HCID 178454858—
SolventDimethylacetamideHCID 31374—
ProductUS10308615, Example 137HCID 134539209—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-e5e4fdc00dcc4b7d82da12d8040b84dd
Source note39k HTE dataset from Pfizer