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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002687Generated: November 1, 2026

4-Chloropyridine-3-carbaldehyde → Methyl 3-formyl-4-pyridinecarboxylate

https://huagongshe.com/reaction/2002687

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloropyridine-3-carbaldehydeHCID 14046674—
ReagentDiisopropylethylamineHCID 81531—
Catalystpalladium(II) acetateHCID 167845—
CatalystBis[2-(diphenylphosphino)phenyl] etherHCID 4285986—
SolventMethanolHCID 887—
ProductMethyl 3-formyl-4-pyridinecarboxylateHCID 97036962—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature130 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3533721fdaa64f778f469dd3169fcbc8
Source note39k HTE dataset from Pfizer