Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002688Generated: November 3, 2026

4-Chloropyridine-3-carbaldehyde → Methyl 3-formyl-4-pyridinecarboxylate

https://huagongshe.com/reaction/2002688

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloropyridine-3-carbaldehydeHCID 14046674—
ReagentDiisopropylethylamineHCID 81531—
Catalyst1,3-Bis(diphenylphosphino)propaneHCID 81219—
Catalystpalladium(II) acetateHCID 167845—
SolventMethanolHCID 887—
ProductMethyl 3-formyl-4-pyridinecarboxylateHCID 97036962—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature130 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-77e09bac17574892ac9f142d3b8b5d27
Source note39k HTE dataset from Pfizer