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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2002896Generated: October 31, 2026

Tert-Butyl isocyanide → HCID 178440944, compound

https://huagongshe.com/reaction/2002896

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-Butyl isocyanideHCID 23577—
Reactant5-Bromo-2-tert-butylpyridineHCID 21041308—
ReactantHCID 178419779HCID 178419779—
ReagentSodium t-butoxideHCID 23676156—
Catalystpalladium(II) acetateHCID 167845—
CatalystDi-tert-butyl(2',4',6'-tris(propan-2-yl)-(1,1'-biphenyl)-2-yl)phosphaneHCID 11618717—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178440944HCID 178440944—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-9d52d54143bc4189b1dbde36dfea85ee
Source note39k HTE dataset from Pfizer