HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 59347032, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 59347040 | HCID 59347040 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59347032 | HCID 59347032 | — |
Reaction Steps
(4S,5S)-Tert-butyl 5-(hydroxymethyl)-4-((2-methoxypyridin-4-yl)methyl)-2,2-dimethyloxazolidine-3-carboxylate (0.281 g, 0.797 mmol) was refluxed in methanol (17 mL) with MeI (0.0798 ml, 1.28 mmol) for 48 hrs. Concentration and purification by silica gel chromotography (20:1 DCM/MeOH) afforded the titled compound along with recovered starting material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745484B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-279136f268954d94b86fc1085e1f49bc |
| Source note | uspto-grants-2010_06 |