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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2003138Generated: October 31, 2026

4-Chloropyridine-3-carbaldehyde → Methyl 3-formyl-4-pyridinecarboxylate

https://huagongshe.com/reaction/2003138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloropyridine-3-carbaldehydeHCID 14046674—
ReagentDiisopropylethylamineHCID 81531—
Catalystpalladium(II) acetateHCID 167845—
CatalystHCID 178454858HCID 178454858—
SolventMethanolHCID 887—
ProductMethyl 3-formyl-4-pyridinecarboxylateHCID 97036962—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-f648a49122e845b7879ec30f00058b4b
Source note39k HTE dataset from Pfizer