Sodium ion → N-Cyclopropyl-3-methoxyaniline

HRID 200337Notes

Reaction equation

HRID 200337 reaction equation
[Br:1][c:2]1[cH:3][c:4]([O:8][CH3:9])[cH:5][cH:6][cH:7]1.[CH3:14][C:15]([CH3:16])([O-:17])[CH3:18].[CH3:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[CH:10]1([NH2:13])[CH2:11][CH2:12]1.[Na+:19].[O:29]=[C:30]([CH:31]=[CH:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[CH:39]=[CH:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1.[O:47]=[C:48]([CH:49]=[CH:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1.[O:65]=[C:66]([CH:67]=[CH:68][c:69]1[cH:70][cH:71][cH:72][cH:73][cH:74]1)[CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1.[Pd:27].[Pd:28]>>[c:2]1([NH:13][CH:10]2[CH2:11][CH2:12]2)[cH:3][c:4]([O:8][CH3:9])[cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 1140TolueneHCID 169713-BromoanisoleHCID 23938Palladium2×HCID 69828CyclopropylamineHCID 95417Dibenzylidene acetone3×HCID 45749132-Methylpropan-2-olate

Product 1

HCID 45091015N-Cyclopropyl-3-methoxyaniline

Sources & evidence

ORD record
ord-d8f190205f554a5180bcbdf9f9f6a1d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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