HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2004418Generated: October 27, 2026
Benzene, 1-ethoxy-2-iodo- → tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate
https://huagongshe.com/reaction/2004418
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzene, 1-ethoxy-2-iodo- | HCID 136415 | — |
| Reactant | (R)-1-Boc-3-hydroxypiperidine | HCID 1514398 | — |
| Reagent | Potassium t-amylate | HCID 23683543 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Catalyst | N,N'-Dimethyl-1,3-propanediamine | HCID 66978 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate | HCID 131737068 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-8b71e876631d45608c2dcd9446f688e5 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
