HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2004419Generated: October 31, 2026
Benzene, 1-ethoxy-2-iodo- → tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate
https://huagongshe.com/reaction/2004419
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzene, 1-ethoxy-2-iodo- | HCID 136415 | — |
| Reactant | (R)-1-Boc-3-hydroxypiperidine | HCID 1514398 | — |
| Reagent | Potassium t-amylate | HCID 23683543 | — |
| Catalyst | 1,10-Phenanthroline | HCID 1318 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate | HCID 131737068 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-bf94f6df61b34f8eb8e31d1cf89a243e |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
