2-(7-amino-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-N,N-dimethylacetamide → 2-[8-[[5-chloro-4-[2-(3-methylpyrrolidin-1-yl)sulfonylanilino]pyrimidin-2-yl]amino]-7-methoxy-1,2,4,5-tetrahydro-3-benzazepin-3-yl]-N,N-dimethylacetamide
Reaction equation
[Cl:21][c:22]1[n:23][cH:24][c:25]([Cl:44])[c:26]([NH:28][c:29]2[c:30]([S:35](=[O:36])(=[O:37])[N:38]3[CH2:39][CH:40]([CH3:43])[CH2:41][CH2:42]3)[cH:31][cH:32][cH:33][cH:34]2)[n:27]1.[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:17][c:18]1[O:19][CH3:20])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[N:14]([CH3:15])[CH3:16])[CH2:9][CH2:10]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:17][c:18]1[O:19][CH3:20])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[N:14]([CH3:15])[CH3:16])[CH2:9][CH2:10]2)[c:22]1[n:23][cH:24][c:25]([Cl:44])[c:26]([NH:28][c:29]2[c:30]([S:35](=[O:36])(=[O:37])[N:38]3[CH2:39][CH:40]([CH3:43])[CH2:41][CH2:42]3)[cH:31][cH:32][cH:33][cH:34]2)[n:27]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-48ec976d3afa4c99bac7debd5f71cd00
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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