Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate → Methyl 6-[3-(benzyloxy)-4-(trifluoromethyl)phenyl]-5-hydroxypyridine-2-carboxylate
Reaction equation
[Br:22][c:23]1[c:24]([OH:33])[cH:25][cH:26][c:27]([C:29](=[O:30])[O:31][CH3:32])[n:28]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([B:19]([OH:20])[OH:21])[cH:12][cH:13][c:14]1[C:15]([F:16])([F:17])[F:18]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](-[c:23]2[c:24]([OH:33])[cH:25][cH:26][c:27]([C:29](=[O:30])[O:31][CH3:32])[n:28]2)[cH:12][cH:13][c:14]1[C:15]([F:16])([F:17])[F:18]Participants
3
Sources & evidence
- ORD record
- ord-806fe6b9e7384cfda162c4a550598e3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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