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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2005442Generated: October 29, 2026

3-Hydroxy-5-methylpyridine → 5-Methylpiperidin-3-ol

https://huagongshe.com/reaction/2005442

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-5-methylpyridineHCID 224753—
ReagentDiisopropylethylamineHCID 81531—
CatalystZincHCID 23994—
Solvent2,2,2-TrifluoroethanolHCID 6409—
Product5-Methylpiperidin-3-olHCID 21278329—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-33fd2b9c556b47028126a80b20eb505a
Source note39k HTE dataset from Pfizer