Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2005445Generated: November 1, 2026

3-Hydroxy-5-methylpyridine → 5-Methylpiperidin-3-ol

https://huagongshe.com/reaction/2005445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-5-methylpyridineHCID 224753—
ReagentHydrochloric AcidHCID 313—
CatalystHCID 178526213HCID 178526213—
Solvent2,2,2-TrifluoroethanolHCID 6409—
Product5-Methylpiperidin-3-olHCID 21278329—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-768aa67e001e4904af97bf7e6dd5d205
Source note39k HTE dataset from Pfizer