Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2005453Generated: October 31, 2026

3-Hydroxy-5-methylpyridine → 5-Methylpiperidin-3-ol

https://huagongshe.com/reaction/2005453

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-5-methylpyridineHCID 224753—
CatalystZincHCID 23994—
Solvent2,2,2-TrifluoroethanolHCID 6409—
Product5-Methylpiperidin-3-olHCID 21278329—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-fe410a956a524d429b8a834d90806fca
Source note39k HTE dataset from Pfizer