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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2005540Generated: November 1, 2026

3-Hydroxy-5-methylpyridine → 5-Methylpiperidin-3-ol

https://huagongshe.com/reaction/2005540

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-5-methylpyridineHCID 224753—
ReagentDiisopropylethylamineHCID 81531—
CatalystHCID 178526213HCID 178526213—
SolventTetrahydrofuranHCID 8028—
Product5-Methylpiperidin-3-olHCID 21278329—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-48c344573a804bc986c8b9d25e3ba8d2
Source note39k HTE dataset from Pfizer