Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2006949Generated: October 30, 2026

(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acid → 4,4,4-Trifluoro-3-phenylbutanoic acid

https://huagongshe.com/reaction/2006949

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acidHCID 2054639—
ReagentMorpholineHCID 8083—
ReagentTriphenylphosphineHCID 11776—
Catalyst(S)-(+)-(3,5-Dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)dimethylamineHCID 10893715—
CatalystHCID 178420233HCID 178420233—
SolventWaterHCID 962—
SolventChloroform-DHCID 71583—
Product4,4,4-Trifluoro-3-phenylbutanoic acidHCID 10376072—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-6b41f91d831440c6a7b5085211e8107f
Source note39k HTE dataset from Pfizer