Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2007000Generated: October 29, 2026

(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acid → 4,4,4-Trifluoro-3-phenylbutanoic acid

https://huagongshe.com/reaction/2007000

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acidHCID 2054639—
ReagentMorpholineHCID 8083—
ReagentTriphenylphosphineHCID 11776—
Catalyst2,2'-((1S,2S)-(+)-1,2-Cyclohexanediylbis((E)(nitrilomethylidyne)))bis(4-(tert-butyl)-6-(4-morpholinylmethyl)phenol), 97HCID 135502777—
CatalystHCID 178420233HCID 178420233—
SolventWaterHCID 962—
SolventChloroform-DHCID 71583—
Product4,4,4-Trifluoro-3-phenylbutanoic acidHCID 10376072—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-2525e2d17aca4a1582ee29c152fb0b87
Source note39k HTE dataset from Pfizer