Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2007031Generated: November 1, 2026

(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acid → 4,4,4-Trifluoro-3-phenylbutanoic acid

https://huagongshe.com/reaction/2007031

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acidHCID 2054639—
Catalyst(2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholaneHCID 16717654—
SolventMethanolHCID 887—
Product4,4,4-Trifluoro-3-phenylbutanoic acidHCID 10376072—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-e9441b7067a2489f97bc4b3ef917fe0e
Source note39k HTE dataset from Pfizer