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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2007059Generated: November 1, 2026

(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acid → 4,4,4-Trifluoro-3-phenylbutanoic acid

https://huagongshe.com/reaction/2007059

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acidHCID 2054639—
Catalyst(1S,2R)-(-)-1-Amino-2-indanolHCID 9866743—
SolventMethanolHCID 887—
Product4,4,4-Trifluoro-3-phenylbutanoic acidHCID 10376072—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-68ca5d5c85de40d68d7734c62e1d6666
Source note39k HTE dataset from Pfizer