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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2007065Generated: October 31, 2026

(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acid → 4,4,4-Trifluoro-3-phenylbutanoic acid

https://huagongshe.com/reaction/2007065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-4,4,4-trifluoro-3-phenylbut-2-enoic acidHCID 2054639—
CatalystN-[(1S,2S)-2-Aminocyclohexyl]-4-methylbenzene-1-sulfonamideHCID 16218314—
SolventMethanolHCID 887—
Product4,4,4-Trifluoro-3-phenylbutanoic acidHCID 10376072—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-ac59e160a5644991bbfda2b9fac35a58
Source note39k HTE dataset from Pfizer