2-Aminopyrimidine-5-boronic acid, pinacol ester → 4-((2-(2-aminopyrimidin-5-yl)-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,N-dimethylpiperazine-1-carboxamide
Reaction equation
[CH3:1][N:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][N:8]([CH2:11][c:12]2[cH:13][c:14]3[c:15]([n:16][c:17]([Cl:26])[n:18][c:19]3[N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[s:27]2)[CH2:9][CH2:10]1)[CH3:28].[CH3:29][C:30]1([CH3:31])[C:32]([CH3:33])([CH3:34])[O:35][B:36]([c:37]2[cH:38][n:39][c:40]([NH2:43])[n:41][cH:42]2)[O:44]1>>[CH3:1][N:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][N:8]([CH2:11][c:12]2[cH:13][c:14]3[c:15]([n:16][c:17](-[c:37]4[cH:38][n:39][c:40]([NH2:43])[n:41][cH:42]4)[n:18][c:19]3[N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[s:27]2)[CH2:9][CH2:10]1)[CH3:28]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c8b0dbc3991344f6a2892172df4a2a2d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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