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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2007864Generated: October 31, 2026

2-(Trifluoromethyl)acrylic acid → (2R)-3,3,3-trifluoro-2-methylpropanoic acid

https://huagongshe.com/reaction/2007864

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)acrylic acidHCID 587694—
ReagentBorate(1-), tetrafluoro-, hydrogen, compd. with 1,1'-oxybis(ethane) (1:1:1)HCID 16211330—
SolventIsopropanolHCID 3776—
Product(2R)-3,3,3-trifluoro-2-methylpropanoic acidHCID 15971430—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-6b54d06b264b4c739fd7ab1e99ab3f12
Source note39k HTE dataset from Pfizer