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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2008987Generated: October 29, 2026

Triethylsilicon → Tert-butyl 4-[7-[5-methyl-1-(oxan-2-yl)indazol-4-yl]-5,6,7,8-tetrahydroquinazolin-4-yl]piperazine-1-carboxylate

https://huagongshe.com/reaction/2008987

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylsiliconHCID 6327258—
ReactantHCID 178422848HCID 178422848—
ReagentDi-tert-butyl peroxideHCID 8033—
CatalystHCID 178447101HCID 178447101—
SolventIsopropanolHCID 3776—
ProductTert-butyl 4-[7-[5-methyl-1-(oxan-2-yl)indazol-4-yl]-5,6,7,8-tetrahydroquinazolin-4-yl]piperazine-1-carboxylateHCID 139388538—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-0a28ec3deb824167953bcf21332c6388
Source note39k HTE dataset from Pfizer