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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2009011Generated: October 31, 2026

HCID 178422848, compound → Tert-butyl 4-[7-[5-methyl-1-(oxan-2-yl)indazol-4-yl]-5,6,7,8-tetrahydroquinazolin-4-yl]piperazine-1-carboxylate

https://huagongshe.com/reaction/2009011

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178422848HCID 178422848—
ReagentHydrochloric AcidHCID 313—
CatalystZincHCID 23994—
SolventAcetic AcidHCID 176—
SolventWaterHCID 962—
ProductTert-butyl 4-[7-[5-methyl-1-(oxan-2-yl)indazol-4-yl]-5,6,7,8-tetrahydroquinazolin-4-yl]piperazine-1-carboxylateHCID 139388538—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-4bc24da13e344a87a52ebba637d670b2
Source note39k HTE dataset from Pfizer