HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(3-Azido-5-fluoropyridin-2-yl)-2,2-dimethylpropanamide | HCID 22293288 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | 3-Azido-5-fluoropyridin-2-amine | HCID 22293242 | — |
Reaction Steps
N-(3-Azido-5-fluoropyridin-2-yl)-2,2-dimethylpropanamide (275 mg, 1.16 mmol) in 3 N HCl (5 mL) was heated to 100° C. After 2 h, the volatiles were removed in vacuo, to give the title compound as its HCl salt (180 mg). MS154.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745427B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-85f631a64d1f456f809694e9f8f1ed62 |
| Source note | uspto-grants-2010_06 |